Recent guidance from the Royal Australasian College of Physicians (RACP) has brought renewed attention to a critical issue in modern medicine: the growing concern around overprescription and what experts call the “prescribing cascade.” This development aligns perfectly with what we…

In recent years, the medical community has significantly advanced in the management of cardiovascular disease, primarily through the lowering of serum cholesterol levels using statins. Despite these advancements, debates continue regarding the optimal dosage of statins, aiming for target cholesterol…

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Determining the best statin dose for a patient often appears challenging. Hitting the ‘sweet spot’, particularly with drugs that affect the brain, can provide enormous relief from symptoms. It is always be prudent to start a new drug with a low…

Website contributor, Professor Simon Dimmitt, has returned as a guest on the podcast, This Medical Life, this time contributing to episode 32, Aspirin: From Poultices To Pills. He was asked back because Aspirin is one of the drugs that features prominently…

The clinical dose response for desired outcomes is often not well established at drug launch. With time, lower doses of many drugs have been found sufficient, with important benefits of greater safety, tolerability and complaince, e.g. pain medicines, antihypertensives, antithrombotics,…

Website contributor, Professor Simon Dimmitt, was a guest on the podcast, This Medical Life. His appearance, on episode 23 entitled, Hypertension: Too Much Of A Good Thing?, provided the opportunity to discuss the concept of correct dosing in relation to hypertension…