Psychotropic Dosing

Effective dose 50% (ED50) = the mean population dose necessary to achieve half the maximum (Emax) possible drug effect. ED50 was estimated from comparative dosing based on reductions in anxiety & related measures and published PET-serotonin transporter EC50 data.
Psychotropics are antagonists and so the mid-part of the dose-response curve plateaus, in contrast to adverse events which continue to increase.

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