Antihypertensive Drug Dosing

Cardiovascular drugs should usually be started around ED50, lower doses are safer and often sufficient, especially in combinations.

Effective dose 50%, ED50 = the mean population dose necessary to achieve half the maximum (Emax) possible drug effect. ED50 was estimated from published dose response data and based on reduction of BP (and with beta-blockers, HR) and thereby hopefully heart failure and other CV outcomes.

This content is for Correct Dosing Professional Access members only.
Login Join Now

Sign up for our mailing list!

Subscription Form